Selected publications

Inflammatory markers (IL-6 and CRP) in childhood and their association with brain structure and psychotic experiences in adulthood
K. Merritt, E. R. Palmer, P. Luque Laguna, …, G. M. Khandaker, R. Upthegrove, G. Lewis, D. Jones, A. S. David
Brain, Behavior, and Immunity (2026)


The impact of cumulative obstetric complications and childhood trauma on brain volume in young people with psychotic experiences
K. Merritt, P. Luque Laguna, A. Sethi, M. Drakesmith, S. A. Ashley, …, A. S. David
Molecular Psychiatry (2023)


Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis
K. Merritt, R. A. McCutcheon, A. Aleman, …, 1H-MRS in Schizophrenia Investigators
Molecular Psychiatry (2023)


Association of age, antipsychotic medication, and symptom severity in schizophrenia with proton magnetic resonance spectroscopy brain glutamate level: a mega-analysis
K. Merritt, P. K. McGuire, A. Egerton, 1H-MRS in Schizophrenia Investigators
JAMA Psychiatry (2021)


Nature of glutamate alterations in schizophrenia: a meta-analysis of proton magnetic resonance spectroscopy studies
K. Merritt, A. Egerton, M. J. Kempton, M. J. Taylor, P. K. McGuire
JAMA Psychiatry (2016)


All publications

Neurometabolites and Antipsychotic Response in Psychosis

2026 · DOI


The association between childhood Toxoplasma gondii, psychotic experiences and grey matter volume: A population-based cohort study

2026 · DOI


Increased Brain-Age Gap in Young Adults With Psychotic Experiences

2026 · DOI


Inflammatory markers (IL-6 and CRP) in childhood and their association with brain structure and psychotic experiences in adulthood

2026 · DOI


1 H-MRS metabolites in antipsychotic-responsive versus non-responsive psychosis: a meta- and mega-analysis

2025 · DOI


Neurometabolites in Antipsychotic-Responsive Versus Non-Responsive Psychosis: A Meta-Analysis

2025 · DOI


PSYSCAN multi-centre study: baseline characteristics and clinical outcomes of the clinical high risk for psychosis sample

2025 · DOI


521. Neurometabolites in Antipsychotic-Responsive Versus Non-Responsive Psychosis: A Meta-Analysis

2025 · DOI


Molecular and micro-architectural mapping of gray matter alterations in psychosis

2025 · DOI


Head circumference trajectories in autism and psychotic experiences

2025 · DOI


A Longitudinal Study of Head Circumference Trajectories in Autism and Autistic Traits

2024 · DOI


Multivariable prediction of functional outcome after first-episode psychosis: a crossover validation approach in EUFEST and PSYSCAN

2024 · DOI


Exploring causal mechanisms of psychosis risk

2024 · DOI


White Matter Microstructure Abnormalities in Individuals at High Risk for Psychosis: A Meta-Analysis of Fractional Anisotropic Changes Associated With Transition to Psychosis

2024 · DOI


Variability and Magnitude of Brain Glutamate Levels in Schizophrenia: A Meta and Mega-Analysis

2024 · DOI


A letter to the editor: The effects of alcohol use on brain glutamate in first episode psychosis

2024 · DOI


The impact of cumulative obstetric complications and childhood trauma on brain volume in young people with psychotic experiences

2023 · DOI


Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis

2023 · DOI


Do brain regions involved in threat processing mediate the association between developmental trauma and psychosis

2023 · DOI


Molecular and micro-architectural mapping of gray matter alterations in psychosis

2023 · DOI


Identifying Electroencephalography Biomarkers in Individuals at Clinical High Risk for Psychosis in an International Multi-Site Study

2022 · DOI


Do brain regions associated with memory processing mediate the relationship between developmental trauma and psychosis?

2022 · DOI


Reduced amygdala volume mediates the association between developmental trauma and psychotic experiences in adulthood – findings from a population-based cohort

2022 · DOI


Variability and Magnitude of Brain Glutamate Levels in Schizophrenia: A Meta And Mega-Analysis

2022 · DOI


Dopamine and glutamate in individuals at high risk for psychosis: a meta‐analysis of in vivo imaging findings and their variability compared to controls

2021 · DOI


Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: a Mega-analysis of Individual Participant-Level Data

2021 · DOI


Longitudinal Structural MRI Findings in Individuals at Genetic and Clinical High Risk for Psychosis: A Systematic Review

2021 · DOI


Symptom Remission and Brain Cortical Networks at First Clinical Presentation of Psychosis: The OPTiMiSE Study.

2020 · DOI


Glyceryl trinitrate in first-episode psychosis unmedicated with antipsychotics: A randomised controlled pilot study.

2020 · DOI


M157. A MULTICENTRE STUDY OF 1H-MRS BRAIN GLUTAMATE LEVELS IN SCHIZOPHRENIA; INVESTIGATING THE EFFECT OF ANTIPSYCHOTIC MEDICATION, SYMPTOM SEVERITY AND AGE

2020 · DOI


T40. GLYCERYL TRINITRATE IN FIRST EPISODE PSYCHOSIS UNMEDICATED WITH ANTIPSYCHOTICS: A RANDOMISED CONTROLLED FEASIBILITY STUDY

2020 · DOI


A MULTICENTRE STUDY OF 1H-MRS BRAIN GLUTAMATE LEVELS IN SCHIZOPHRENIA; INVESTIGATING THE EFFECT OF ANTIPSYCHOTIC MEDICATION, SYMPTOM SEVERITY AND AGE

2020 ·


Towards Precision Medicine in Psychosis: Benefits and Challenges of Multimodal Multicenter Studies-PSYSCAN: Translating Neuroimaging Findings From Research into Clinical Practice

2020 · DOI


Remission from antipsychotic treatment in first episode psychosis related to longitudinal changes in brain glutamate.

2019 · DOI


REMISSION FROM ANTIPSYCHOTIC TREATMENT IN FIRST EPISODE PSYCHOSIS RELATED TO LONGITUDINAL CHANGES IN BRAIN GLUTAMATE LEVELS

2019 · DOI


Response to initial antipsychotic treatment in first episode psychosis is related to anterior cingulate glutamate levels: a multicentre 1H-MRS study (OPTiMiSE)

2018 · DOI


Effects of Antipsychotic Administration on Brain Glutamate in Schizophrenia: A Systematic Review of Longitudinal 1H-MRS Studies

2017 · DOI


SA83. Brain Glutamate Levels and Antipsychotic Response in Schizophrenia

2017 · DOI


BRAIN GLUTAMATE LEVELS AND ANTIPSYCHOTIC RESPONSE IN SCHIZOPHRENIA

2017 ·


NATURE OF GLUTAMATE ALTERATIONS IN SCHIZOPHRENIA: A META-ANALYSIS OF PROTON MAGNETIC RESONANCE SPECTROSCOPY STUDIES

2017 ·


Nature of Glutamate Alterations in Schizophrenia: A Meta-analysis of Proton Magnetic Resonance Spectroscopy Studies.

2016 · DOI


Relationship Between Brain Glutamate Levels and Clinical Outcome in Individuals at Ultra High Risk of Psychosis

2014 · DOI


RELATIONSHIP BETWEEN BRAIN GLUTAMATE CONCENTRATIONS AND FUNCTIONAL OUTCOME IN INDIVIDUALS AT ULTRA HIGH RISK OF PSYCHOSIS

2014 · DOI


THE REPRODUCIBILITY OF 1H-MRS GLUTAMATE CONCENTRATION ESTIMATES AT 3 TESLA, IMPLICATIONS FOR GLUTAMATE IMAGING IN SCHIZOPHRENIA

2014 · DOI


Relationship between glutamate dysfunction and symptoms and cognitive function in psychosis

2013 · DOI


The Effect of Developmental Trauma on Brain Structures Involved in Threat and Memory Processing and Its Relation to Psychotic Experiences in Adulthood

· DOI